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杨闯作者: 来源: 时间:[2021-04-26]
温州医科大学附属第一医院精神卫生科主任、儿童精神科主任。国家住院医师规范化培训温州医科大学附属第一医院基地负责人、督导专家、导师。国家临床药物研究温州医科大学附属第一医院精神科基地负责人PI。四川大学华西精神病学医学博士,中南大学精神病学医学硕士,昆明医科大学临床医学学士。意大利弗洛伦撒卫生署(Mayer儿童医院)访问学者。中国认知科学学会神经与精神影像专业委员会委员,中华医学会行为医学分会预防行为医学学组委员,中国医师协会强迫症专业委员会委员,中华医学会温州精神病学分会副主任委员,规划本科教材《儿童少年期精神病学》编委。
1.专业研究方向:儿童精神医学 2.所获成果(包括科研成果奖、专利、专著等) (1)科研项目: 1.浙江省自然基金,Y20H090066,破坏性心境失调障碍大脑奖赏机制异常的神经心理与磁共振影像研究 ,2020-1-1至2022-12-31,主持。 2浙江省自然基金,LY14H090012,基于多模态磁共振成像的孤独谱系障碍脑网络微结构特征及危险基因相关性初探,2014/1-2017/12,8.5万元,已结题,主持。3.浙江省自然基金,LY14H180006,儿童注意缺陷多动障碍静息态功能磁共振与多巴胺功能系统基因多态性的相关性研究,2014/1-2017/12,8.0万元,已结题,参加。 4.国家自然科学基金,30470624 ,注意缺陷多动障碍烟碱受体基因多态性及哌甲酯对SHR鼠影响的烟碱受体机制研究,2005/1-2007/12,20万元,已结题,参加。 3.发表论文(具有代表性的5篇) 1. Lin H, Lin Q, Li H, Wang M, Chen H, Liang Y, Bu X, Wang W, Yi Y, Zhao Y, Zhang X, Xie Y, Du S, Yang C, Huang X. Functional Connectivity of Attention-Related Networks in Drug-Naive Children With ADHD. Journal of attention disorders. 2018:1087054718802017-1087054718802017. 2. Lin Q, Bu X, Wang M, Liang Y, Chen H, Wang W, Yi Y, Lin H, Zhou J, Lu L, Hu X, Yang C, Huang X. Aberrant white matter properties of the callosal tracts implicated in girls with attention-deficit/hyperactivity disorder. Brain imaging and behavior. 2018. 3. Ming Zhou CY, Xuan Bu, Yan Liang, Haixi Lin, Xinyu Hu, Hong Chen, Meihao Wang, Xiaoqi Huang. Abnormal Functional Network Centrality in Drug-Naïve Boys with Attention-Deficit/Hyperactivity Disorder. European Child and Adolescent Psychiatry. 2019. 4. Liao Y, Huang X, Wu Q, Yang C, Kuang W, Du M, Lui S, Yue Q, Chan RCK, Kemp GJ, Gong Q. Is depression a disconnection syndrome? Meta-analysis of diffusion tensor imaging studies in patients with MDD. Journal of Psychiatry & Neuroscience. 2013;38:49-56. 5. Guo T, Chen H, Liu B, Ji W, Yang C. Methylenetetrahydrofolate Reductase Polymorphisms C677T and Risk of Autism in the Chinese Han Population. Genetic Testing and Molecular Biomarkers. 2012;16:968-973. 6. Guo T, Yang C, Guo L, Liu K. A comparative study of the effects of ABT-418 and methylphenidate on spatial memory in an animal model of ADHD. Neuroscience Letters. 2012;528:11-15. 7. Guo T, Wang W, Liu B, Chen H, Yang C. Catechol-O-methyltransferase Val158Met polymorphism and risk of autism spectrum disorders. Journal of International Medical Research. 2013;41:725-734. 8. Qian A, Tao J, Wang X, Liu H, Ji L, Yang C, Ye Q, Chen C, Li J, Cheng J, Wang M, Zhao K. Effects of the 2-Repeat Allele of the DRD4 Gene on Neural Networks Associated With the Prefrontal Cortex in Children With ADHD. Frontiers in Human Neuroscience. 2018;12. 9. Qian A, Wang X, Liu H, Tao J, Zhou J, Ye Q, Li J, Yang C, Cheng J, Zhao K, Wang M. Dopamine D4 Receptor Gene Associated with the Frontal-Striatal-Cerebellar Loop in Children with ADHD: A Resting-State fMRI Study. Neuroscience Bulletin. 2018;34:497-506. 10. Zhou J, Gao Y, Bu X, Li H, Liang Y, Chen H, Wang M, Lin F, Yang C, Huang X. A multi-parameter resting-state functional magnetic resonance imaging study of brain intrinsic activity in attention deficit hyperactivity disorder children. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi. 2018;35:415-420.
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