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李新民作者: 来源: 时间:[2020-05-03]
教授、博士生导师,加拿大阿尔伯塔大学医学与口腔学院副院长、精神病学系主任主持承担精神病学领域代表性科研项目30余项,发表相关科研论文100余篇,论文H指数达到49,发明专利4项,担任美国和加拿大CIHR等多项基金的评阅人。招收学术型精神病与精神卫生学硕士研究生。 1.专业研究方向:精神疾病的神经机制 2.所获成果(包括科研成果奖、专利、专著等) ①John R. Evans Leaders Fund:Interrogating neuronal network dysfunction in models of neuropsychiatric or neurological diseases. Canada Foundation for Innovation. (2015,主持) ②CIHR-MHRC – Regional Partnership Program:Oligodendrocyte dysfunction in schizophrenia: mechanism and target of treatment.(2012-2014,主持) ③CIHR: China-Canada Joint Initiative:A mechanistic study of major depressive disorder: role of oligodendrocytes.(2011-2014,主持) ④CIHR Operating Grant: Health Effects of the Alberta:The health effects of the Alberta wildfire and evacuation: Pediatric resiliency.(2016-2018,参与) ⑤CIHR/NSFC GACD Mental Health Call:Enhanced Measure-Based care Effectiveness for Depression (2018-2022,参与) 3.发表论文(具有代表性的5篇) ①Li, XM (通讯作者) . Quetiapine facilitates oligodendrocyte development and prevents mice from myelin breakdown and behavioral changes. Molecular Psychiatry. 13(7):697-708.(IF=12.439,TOP期刊,被引100次) ②Li, XM (通讯作者). The response of synaptophysin and microtubule-associated protein 1 to restraint stress in rat hippocampus and its modulation by venlafaxine. Journal of Neurochemistry. 91(6):1380-1388.(IF=4.319,TOP期刊,被引47次) ③Li, XM (通讯作者). Dose-related effects of chronic antidepressants on neuroprotective proteins BDNF, bcl-2 and Cu/Zn-SOD in rat hippocampus. Neuropsychopharmacology. 28(1):53-62. (IF=6.782,TOP期刊,被引128次) ④Li, XM (通讯作者). The ability of atypical antipsychotic drugs vs. haloperidol to protect PC12 cells against MPP+-induced apoptosis. European Journal of Neuroscience . 17(8):1563-1570. (IF=3.090,被引106次) ⑤Li, XM (通讯作者). Olanzapine protects PC12 cells from oxidative stress induced by hydrogen peroxide. Journal of Neuroscience Reasearch.73(3):364-368. (IF=2.549,被引88次)
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