蔡翔

姓名：蔡翔  职称：研究员  学历：研究生  学位：博士

蔡翔，博士、教授、现任瓯江实验室研究员。入选浙江省海外引才“创新长期”项目。曾分别在马里兰大学和南伊利诺伊大学任助理教授和长聘副教授（获终 身教职）。长期从事抑郁症病理及抗抑郁药药理的研究。以第一作者或通讯作者在 Nature Neuroscience, Neuron, Science Signaling 和 Journal of Neuroscience 等知名期刊发 表论文多篇。主持NIHRO1, NIH R56基金及中国国家自然科学基金多项，获得美国脑与行为基金会青年学者奖。是抑郁症兴奋性突触假 说的提出者和主要贡献人。近年来的工作主要集中在快速抗抑郁药物机制研究和开发。

代表性文章： 

1. Brager DH, Cai X, and Thompson SM. Activity-dependent activation of presynaptic protein kinase C mediates post-tetanic potentiation； Nature Neuroscience, 6: 551-552，2003 

2. Cai X, Liang CW, Muralidharan S, Kao JP Y, Tang CM, and Thompson SM. Unique roles of SK and Kv4.2 potassium channels in dendritic integration. Neuron, 44: 351-364, 2004

3. Cai X, Wei DS, Gallagher SE, Bagal A, Mei YA, Kao JP Y, Thompson SM, and Tang CM. Hyperexcitability of distal dendrites in hippocampal pyramidal cells following chronic partial deafferentation. Journal of Neuroscience, 27:59-68, 2007

4. Cai X, Kallarackal AJ, Kvarta MD, Goluskin S, Gaylor K, Bailey AM, Lee HK, Huganir RL, Thompson SM. Local potentiation of excitatory synapses by serotonin and its dysregulation in rodent models of depression. Nature Neuroscience, 16:464-72, 2013

5. Zhang K, Xu T, Yuan ZM, Wei ZS, Yamaki VN, Huang MF, Huganir RL, and Cai X. The Essential Roles of GluR1 Phosphorylation and Presynaptic NMDA Receptor Inhibition in Fast-acting Antidepressant Responses of Ketamine. Science Signaling， 9(458): ra123, 2016 (Cover Story)